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Petawali (Tinospora crispa)

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Common names

-Akar patawali, putarwali, petawali, daun akar wali, batang wali, akar seruntum (Malay)

-Heavenly elixir, heartleaf moonseed (English)

-Bo ye qing niu dan (Chinese)

-Kattukkodi (Tamil)

Description

-belongs to Menispermaceae family

-an herbaceous vine which extensively grows in tropical and subtropical regions of Southeast Asia

-The old stems of T. crispa are fleshy, with prominent blunt tubercles whereas younger stems are slightly fleshy, thin epidermis, membranous, brownish, and glabrous.

-leaves are large, heart shaped 6–12 cm long and 7–12 cm wide.

-Petioles are glabrous and 5–15 cm long

-Leaf blade is slightly fleshy, both surfaces glabrous and very delicate when dried

-The fruit is 7–8 mm in length.

Chemical contituents

Flavone and flavone glycosides

-apigenin, diosmetin (luteolin 4’-methyl ether), genkwanin, luteolin 4’-methyl ether 7-glucosides, genkwanin 7-glucosides, luteolin 4’-methyl ether 3’-glucoside

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Triterpenes 

-cycloeucalenol, cycloeucalenone, 

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Diterpenes and diterpene glucosides

-tinocrispol A, borapetol A, 2-O-lactoylborapetoside B, 6’-O-lactoylborapetoside B, borapetoside A, borapetoside B, borapetoside C, borapetoside D, borapetoside E, borapetoside F, borapetoside G, borapetoside H, rumphioside A, rumphioside B, syringin, columbin

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Alkaloids 

-N-formylasimilobine 2-O-β-D-glucopyranoside, magnoflorine, N-demethyl-N-formyldehydronornuciferine, N-formylanonaine, N-acetylanonaine, N-formylnornuceferine, N-acethyllnornuceferine, lysicamine, tyramine, higenamine, N-cis-feruloyltyramine, N-trans-feruloyltyramine, paprazine, N-trans-caffeoyltyramine, 4,13-dihydroxy-2,8,9-trimethoxydibenzo(a,g)quinolizinium, columbamine, dihydrodiscretamin, palmatine, jatrorrhizine, berberine, salsolinol

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Lignan

-secoisolariciresinol, syringaresinol, adenosine, uridine, adenine

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Sterol

-β-sitosterol, stigmasterol, makisterone C

Traditional uses 

Preparation/ part of plants used

  • to treat high blood pressure

Stem: cut 0.5 cm of the stem ad should be eaten with betel (sirih) or banana once a week

  • to treat diabetes

Stem: boiled and mixed with stink bean root (akar  petai) and jering root and drink it twice a week

Stem: dried, grinded and put in capsules (should be eaten everyday)

  • to abort a child

Stem: grinded and rubbed on the stomach

  • to avoid arthritis (bone pain)

Stem

  • to treat malaria

Stem: dried, boiled and drink 

Root 

  • to relieve pain

Stem  powder: applied to the  part of the body

  • to treat cholera and deworming medicine

Stem/whole plant: infusion

  • used as antiseptic (clean blood)

Whole plant: decoction

  • to treat hypertension and malaria

Whole plant: boiled and drink it

  • to cure rheumatism

Root: poultice made by pounding T. crispa root with rice wash and charred coconut husks

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